Portal 2's Wheatley did not win an award at the Spike VGAs. Mildly disappointing, but then, given the Spike's themselves are mildly disappointing, I'm not losing much sleep over it.
Eeexxcccceeepppptttt for this. Being a virtual character, Valve had to make his acceptance speech in advance. Just in case he actually won. He didn't, but the speech exists, and here it is.
If Wheatley Had Won [Rock, Paper, Shotgun]